Postpartum Cerebral Venous Sinus Thrombosis: A Case Report

Introduction: Cerebral venous thrombosis (CVT) remains one of the most frequent cause of stroke in young adults although it is
a rare disorder. It has a serious emergency manifestation during pregnancy and postpartum. It is frequently under diagnosed and
limited publications in developing countries especially sub-Saharan Africa.
Case Presentation: Here, we report the case of a 35-year-old female, para 8 and gravida 8, brought to emergency department on her
ninth day postpartum, having severe headaches and confusion; during her admission to emergency, she suffered two episodes of
generalized seizure. On admission, the patient's blood pressure was 200/120 mmHg. The patient was firstly diagnosed with postpartum
eclampsia and managed with magnesium sulfate for seizures and hydralazine for blood pressure control. On ward admission, she
continued having seizures and her level of consciousness decreased with left side weakness. An urgent MRI of head and MR
venography performed immediately revealed acute thrombosis involving the anterior aspect of superior sagittal sinus and the left
transverse sinus. The patient was moved to the ICU. Anti-coagulant LMW enoxaparin and anticonvulsant were started. After
improving on clinical and biochemical tests, the patient was transferred to the inpatient ward on fifth day. Another two days later
in the ward, she improved significantly, and then a head CT (contrast) angiography/venography was performed before she was
discharge and showed no evidence of filling defect in cortical/dural venous sinuses.
Conclusion: Cerebral venous sinus thrombosis (CVST) and postpartum eclampsia may have similar manifestations in young women
of reproductive age. Early prompt diagnosing and therapeutic intervention of CVST can prevent further neurological deterioration and
immediately improve the patient